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Cyclobenzaprine: What Is It? Side Effects & Interactions Cleveland Clinic

Alcohol alone is a CNS depressant; taken together with Benadryl, it can increase the sedating effect of Benadryl, thus worsening drowsiness. So if you drink alcohol while taking is flexeril dangerous Benadryl, you will feel extremely sleepy. Drinking alcohol while on Benadryl can also lead to other side effects like dizziness, confusion, and slowed breathing rate.

These effects may be especially severe in elderly individuals who may also experience impaired judgment and coordination. The FAA does not maintain a list ofacceptable medications. Pilot performance is affected by both the underlying medical condition(s) and medication (s); we must consider both in individual cases.

Will Flexeril Show Up on a Drug Test?

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. Older adults may be more sensitive to the side effects of this drug, especially drowsiness, confusion, constipation, or trouble urinating. Drowsiness and confusion can increase the risk of falling. Flexeril has active ingredients of cyclobenzaprine hydrochloride. EHealthMe is studying from 36,937 Flexeril users for its effectiveness, alternative drugs and more. Benadryl has active ingredients of diphenhydramine hydrochloride.

The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

  • I thought I saw someone standing in my bedroom, and it looked like a child.
  • The FAA does not maintain a list of acceptable medications.
  • Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects.
  • The composite primary outcome of death, ED visit or hospitalization within 1-year of cohort entry occurred in 320,513 patients (17.7%).

Children may be more sensitive to the side effects of this drug. This drug can often cause excitement in young children instead of drowsiness. If your doctor has directed you to use this medication, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medication affects you. Do not stand or sit up quickly, especially if you are an older patient. Alcohol may interfere with the effect of this medication.


In addition to drug interactions with the medicines listed above, other drugs may also interact with Benadryl. If you take medications for certain medical conditions, give your healthcare professional a complete list of your other drugs. Your doctor or pharmacist will make sure that all your medications are appropriate and that no known drug interactions exist.

Do not use this product to treat cold symptoms in children younger than 6 years unless specifically directed by the doctor. Some products (such as long-acting tablets/capsules) are not recommended for use in children younger than 12 years. Ask your doctor or pharmacist for more details about using your product safely.These products do not cure or shorten the length of the common cold and may cause serious side effects. To decrease the risk for serious side effects, carefully follow all dosage directions. Do not give other cough-and-cold medication that might contain the same or similar ingredients (see also Drug Interactions section).

Diphenhydramine Oral: Uses, Side Effects, Interactions, Pictures … – WebMD

Diphenhydramine Oral: Uses, Side Effects, Interactions, Pictures ….

Posted: Thu, 04 Sep 2014 13:42:05 GMT [source]

Although there appears to be insufficient data on metaxalone and methocarbamol, these may be useful in patients who cannot tolerate the sedative properties of cyclobenzaprine or tizanidine. Of note, methocarbamol costs substantially less than metaxalone. Taking Benadryl along with other antihistamines can increase the risk of side effects. This includes drugs like meclizine (Antivert), loratadine (Claritin), cetirizine (Zyrtec), hydroxyzine (Vistaril), and promethazine (Promethegan).

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Because older adults often experience chronic health conditions that require treatment with multiple medications, there is a greater likelihood of experiencing unwanted drug side effects. Older people can also be more sensitive to certain medications. Check with your doctor right away if you have anxiety, restlessness, a fast heartbeat, fever, sweating, muscle spasms, twitching, nausea, vomiting, diarrhea, or see or hear things that are not there. These may be symptoms of a serious condition called serotonin syndrome.

Before taking cyclobenzaprine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Take this medication by mouth with or without food as directed by your doctor. Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase. It is based on diphenhydramine hydrochloride and cyclobenzaprine hydrochloride (the active ingredients of Benadryl and Flexeril, respectively), and Benadryl and Flexeril (the brand names).


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